Substance may block cancer cell growth

COLUMBUS, Ohio (UPI) — A substance produced when eating broccoli and Brussels sprouts may block the growth of cancer cells, U.S. researchers say.

Scientists at the Ohio State University Comprehensive Cancer Center say study evidence suggests the substance, indole-3-carbinol, known as I3C, may have anti-cancer effects, a university release said Tuesday.

The laboratory study discovered a connection between I3C and a molecule called Cdc25A, which is essential for cell division and proliferation, the release said.

“Cdc25A is present at abnormally high levels in about half of breast cancer cases, and it is associated with a poor prognosis,” says study leader Xianghong Zou, assistant professor of pathology at the Ohio State University Medical Center.

The study, published in the journal Cancer Prevention Research, said I3C destroyed the molecule and blocked the growth of breast cancer cells.

The molecule also occurs at abnormally high levels in cancers of the prostate, liver, esophagus, endometrium and colon, in non-Hodgkin lymphoma, and in other diseases such as Alzheimer’s disease, Xianghong noted.

“I3C can have striking effects on cancer cells,” he said, “and a better understanding of this mechanism may lead to the use of this dietary supplement as an effective and safe strategy for treating a variety of cancers and other human diseases.”

Copyright 2010 by United Press International

Sourced & published by Henry Sapiecha

Dying of Leukemia, With No Scientific Credentials, John Kanzius Invents an Exciting New Approach to Treating Cancer

CBS show 60 Minutes profiled John Kanzius–retired broadcast executive, dying leukemia patient, and self-taught inventor. Kanzius has invented a new approach to cancer therapy. In his Florida garage, he has spent hundreds of thousands of dollars of his own money, to improve his focused RF thermal therapy for cancer.

In collaboration with surgical oncologist Steven Curley at MD Anderson Medical Center in Texas, Kanzius has worked against time–his own slow losing battle with leukemia–to develop a safe and effective therapy that could start saving lives.Kanzius suspected that nano-particles of metal might work particularly well for receiving the heat from the RF energy, and heating tumours. So oncologist Curley contacted nanotechnolgist Richard Smalley–Nobel Prize winning discoverer of the buckyball–to request a vial of Smalley’s nanoparticles to test Kanzius’ theory in mice. Although Smalley was highly skeptical of Kanzius’ intuition–he said the idea “wouldn’t work”–Curley and Kanzius proceeded to test Smalley’s nanoparticles in the mice. The RF + nanoparticle approach worked brilliantly.

So we have yet another example where experts are proven wrong by amateur scientists and inventors!

Richard Smalley initially thought that the radiowave to heat up metal nanoparticle technique to cook cancer tumors would not work. Richard’s scientific intuition was that this would completely fail. He was converted into being a believer when proven wrong with successful experimentation. __NextBigFuture

And sadly, Richard Smalley himself died of lymphoma not long after changing his mind about Kanzius RF cancer tx.

Kanzius himself expects no personal benefit to ever come to him from his hard work and years of toil on RF thermal cancer therapy. But he hopes to live long enough to see the first patient successfully treated by his device.

But if this one does work, it most likely won’t be developed in time to help the man who invented it. John Kanzius may have the option of a bone marrow transplant that could buy him more time, but after six years of chemo it would be another grueling ordeal.

“Did you ever say, ‘I’m not going to do this anymore. I’m not going to put myself through it,’?” Stahl asked.

“Yes. I said that-only about a year and a half ago,” Kanzius replied. “I changed my mind because I think with all the research that’s going on with the institutions, that maybe, I’d like to be around for the first patient to get treated and just have a smile.”

“Oh my God,” Stahl said.

“And then I don’t care anymore,” Kanzius replied. __60Minutes

CBS News web story on Kanzius

Sourced and published by Henry Sapiecha 19th Jan 2010

INDIAN ALMOND TREE

TERMINALIA CATAPPA

Cultivation and uses

Terminalia catappa is widely grown in tropical regions of the world as an ornamental tree, grown for the deep shade its large leaves provide. The fruit is edible, tasting slightly acidic.

The wood is red, solid and has high water resistance; it has been utilized in Polynesia for making canoes. in telugu it is called as

BADAM CHETTU

The leaves contain several flavonoids (like kamferol or quercetin), several tannins (such as punicalin, punicalagin or tercatin), saponines and phytosterols. Due to this chemical richness, the leaves (and also the bark) are used in different traditional medicines for various purposes. For instances, in Taiwan fallen leaves are used as a herb to treat liver diseases. In Suriname, a tea made from the leaves is prescribed against dysentery and diarrhea. It is also thought that the leaves contain agents for prevention of cancers (although they have no demonstrated anticarcinogenic properties) and antioxidant as well as anticlastogenic characteristics.

www.sciencearticlesonline.com

Keeping the leaves in an aquarium is said to lower the pH and heavy metal content of the water It has been utilized in this way by Betta breeders in Thailand for many years

Sourced and Published by Henry Sapiecha 5th Oct 2009